Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Tubulointerstitial nephritis
ADR ID BADD_A04682
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.02      Nephritis NEC
20.05.02.002      Tubulointerstitial nephritis
Description Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction. [MeSH]
MedDRA Code 10048302
MeSH ID D009395
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute interstitial nephritis | Chronic interstitial nephritis | Interstitial nephritis acute | Interstitial nephritis chronic | Nephritis interstitial | Nephritis interstitial acute | Nephritis interstitial chronic | Renal interstitium disorder | Tubulointerstitial nephritis | Renal tubulitis | Nephritis, Interstitial | Interstitial Nephritis | Interstitial Nephritides | Nephritides, Interstitial | Nephritis, Tubulointerstitial | Nephritides, Tubulointerstitial | Tubulointerstitial Nephritides | Tubulointerstitial Nephritis
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00941Flurbiprofen0.014548%
BADD_D00967Fosinopril--
BADD_D00979Furosemide0.000349%
BADD_D01009Gemcitabine0.004529%
BADD_D01016Gentamicin0.002754%
BADD_D01042Griseofulvin0.005116%
BADD_D01048Guanidine--
BADD_D01049Guanidine hydrochloride--
BADD_D01081Hydralazine0.001657%
BADD_D01083Hydrochlorothiazide0.000044%
BADD_D01119Ibrutinib--
BADD_D01120Ibuprofen--
BADD_D01133Ifosfamide0.001598%
BADD_D01136Imatinib--
BADD_D01149Indapamide--
BADD_D01150Indinavir--
BADD_D01151Indinavir sulfate--
BADD_D01156Indomethacin--
BADD_D01167Interferon alfa-2b--
BADD_D01194Irbesartan--
BADD_D01204Isoniazid0.038222%
BADD_D01213Isotretinoin0.003157%
BADD_D01217Itraconazole0.009282%
BADD_D01231Ketoprofen0.016556%
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01243Lamotrigine0.001418%
BADD_D01245Lansoprazole0.002095%
BADD_D01252Leflunomide0.000808%
BADD_D01253Lenalidomide--
The 4th Page    First    Pre   4 5 6 7 8    Next   Last    Total 8 Pages